作者: Stefano Geuna
DOI: 10.1016/J.JNEUMETH.2015.01.021
关键词: Sciatic nerve injury 、 Experimental model 、 Sciatic nerve 、 Sciatic Neuropathy 、 Nerve repair 、 Peripheral nerve 、 Neuroscience 、 Regeneration (biology) 、 Medicine 、 Clinical research
摘要: In the pre-clinical view, study of peripheral nerve repair and regeneration still needs to be carried out in animal models due structural complexity this organ which can only partly simulated vitro. The far most used experimental model is based on injury sciatic nerve, largest trunk mammals. paper, potential application research critically reviewed. This paper aimed at helping researchers properly employing vivo for as well interpreting results a clinical translation perspective.