The role of cholesterol metabolism and cholesterol transport in carcinogenesis: a review of scientific findings, relevant to future cancer therapeutics.
作者： Pedro M. R. Cruz , Huanbiao Mo , Walter J. McConathy , Nirupama Sabnis , Andras G. Lacko
关键词: Hormone 、 Cancer cell 、 Context (language use) 、 Carcinogenesis 、 Cancer 、 Pharmacology 、 Steroid 、 Lipoprotein transport 、 Cholesterol 、 Biology
摘要: … The purpose of this review is to provide an up to date assessment of the findings involving cholesterol metabolism and transport with a focus on opportunities for cancer therapeutics …
frontiersin.org
core.ac.uk
sci-hub.se 参考文章(84)
N I Azrolan, P S Coleman, A discoordinate increase in the cellular amount of 3-hydroxy-3-methylglutaryl-CoA reductase results in the loss of rate-limiting control over cholesterogenesis in a tumour cell-free system Biochemical Journal. ,vol. 258, pp. 421- 425 ,(1989) , 10.1042/BJ2580421
S Vitols, G Gahrton, A Ost, C Peterson, Elevated Low Density Lipoprotein Receptor Activity in Leukemic Cells With Monocytic Differentiation Blood. ,vol. 63, pp. 1186- 1193 ,(1984) , 10.1182/BLOOD.V63.5.1186.1186
H. W. Chen, A. A. Kandutsch, H. J. Heiniger, The role of cholesterol in malignancy. Progress in Experimental Tumor Research. ,vol. 22, pp. 275- 316 ,(1978) , 10.1159/000401203
Mian M.K. Shahzad, Lingegowda S. Mangala, Hee Dong Han, Chunhua Lu, Justin Bottsford-Miller, Masato Nishimura, Edna M. Mora, Jeong-Won Lee, Rebecca L. Stone, Chad V. Pecot, Duangmani Thanapprapasr, Ju-Won Roh, Puja Gaur, Maya P. Nair, Yun-Yong Park, Nirupama Sabnis, Michael T. Deavers, Ju-Seog Lee, Lee M. Ellis, Gabriel Lopez-Berestein, Walter J. McConathy, Laszlo Prokai, Andras G. Lacko, Anil K. Sood, Targeted delivery of small interfering RNA using reconstituted high-density lipoprotein nanoparticles. Neoplasia. ,vol. 13, pp. 309- 319 ,(2011) , 10.1593/NEO.101372
Huanbiao Mo, Charles E. Elson, Studies of the isoprenoid-mediated inhibition of mevalonate synthesis applied to cancer chemotherapy and chemoprevention. Experimental Biology and Medicine. ,vol. 229, pp. 567- 585 ,(2004) , 10.1177/153537020422900701
Kenneth K. Ng, Jonathan F. Lovell, Gang Zheng, Lipoprotein-inspired nanoparticles for cancer theranostics. Accounts of Chemical Research. ,vol. 44, pp. 1105- 1113 ,(2011) , 10.1021/AR200017E
Deema Hussein, Huanbiao Mo, d-δ-Tocotrienol-Mediated Suppression of the Proliferation of Human PANC-1, MIA PaCa-2, and BxPC-3 Pancreatic Carcinoma Cells Pancreas. ,vol. 38, pp. e124- e136 ,(2009) , 10.1097/MPA.0B013E3181A20F9C
Julie Dufour, Emilie Viennois, Hugues De Boussac, Silvère Baron, Jean-Marc Lobaccaro, Oxysterol receptors, AKT and prostate cancer. Current Opinion in Pharmacology. ,vol. 12, pp. 724- 728 ,(2012) , 10.1016/J.COPH.2012.06.012
J. W. Clendening, A. Pandyra, P. C. Boutros, S. E. Ghamrasni, F. Khosravi, G. A. Trentin, A. Martirosyan, A. Hakem, R. Hakem, I. Jurisica, L. Z. Penn, Dysregulation of the mevalonate pathway promotes transformation Proceedings of the National Academy of Sciences of the United States of America. ,vol. 107, pp. 15051- 15056 ,(2010) , 10.1073/PNAS.0910258107
Andras G. Lacko, Maya Nair, Sulabha Paranjape, Linda Mooberry, Walter J. McConathy, Trojan horse meets magic bullet to spawn a novel, highly effective drug delivery model. Chemotherapy. ,vol. 52, pp. 171- 173 ,(2006) , 10.1159/000093268