['ASIA' - Autoimmune/inflammatory syndrome induced by adjuvants: even and odd].

作者: C. Perricone , C. Alessandri , G. Valesini

DOI: 10.4081/REUMATISMO.2011.63

关键词: Gulf War syndromeMacrophagic myofasciitisMedicineEnvironmental exposureAutoimmune/inflammatory syndrome induced by adjuvantsAutoimmunityImmune systemSigns and symptomsAdjuvantImmunology

摘要: Recently, Shoenfeld and Agmon-Levin described a potential new syndrome, namely ASIA - autoimmune/inflammatory syndrome induced by adjuvants, that comprises four medical conditions: siliconosis, the Gulf war macrophagic myofasciitis post-vaccination phenomena, characterized hyperactive immune responses accompanied similar complex of signs symptoms. Most relevantly, these conditions share linkage represented adjuvants. This common soil may possibly induce autoimmune or auto-inflammatory diseases in humans as it was demonstrated different animal models. Reconsidering under unified umbrella this apparently detached condition is not only intriguing, but also provocative, help unraveling novel pathogenetic mechanisms, preventive measures, therapeutic targets.

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