Primate models of movement disorders of basal ganglia origin
作者： Mahlon R. DeLong
DOI: 10.1016/0166-2236(90)90110-V
关键词: Indirect pathway of movement 、 Hemiballismus 、 Movement disorders 、 Direct pathway of movement 、 Basal ganglia 、 Basal ganglia disease 、 Psychology 、 Premovement neuronal activity 、 Neuroscience 、 Subthalamic nucleus
摘要: Movement disorders associated with basal ganglia dysfunction comprise a spectrum of abnormalities that range from the hypokinetic (of which Parkinson's disease is best-known example) at one extreme to hyperkinetic (exemplified by Huntington's and hemiballismus) other. Both extremes this movement disorder can be accounted for postulating specific disturbances within ganglia-thalamocortical 'motor' circuit. In paper, Mahlon DeLong describes changes in neuronal activity motor circuit animal models hypo- disorders.
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