C-H bond activation enables the rapid construction and late-stage diversification of functional molecules

作者: Joanna Wencel-Delord , Frank Glorius

DOI: 10.1038/NCHEM.1607

关键词: Late stageSmall moleculeChemistryDiversification (marketing strategy)Functional importanceNanotechnologyCarbon chemistryRapid constructionC h bond

摘要: The beginning of the twenty-first century has witnessed significant advances in the field of C–H bond activation, and this transformation is now an established piece in the synthetic …

参考文章(54)
Tae Soo Jo, Se Hye Kim, Jihoon Shin, Chulsung Bae, Highly efficient incorporation of functional groups into aromatic main-chain polymer using iridium-catalyzed C-H activation and suzuki-miyaura reaction. Journal of the American Chemical Society. ,vol. 131, pp. 1656- 1657 ,(2009) , 10.1021/JA808374E
Takanori Matsuda, Sho Kadowaki, Tsuyoshi Goya, Masahiro Murakami, Synthesis of Silafluorenes by Iridium-Catalyzed [2 + 2 + 2] Cycloaddition of Silicon-Bridged Diynes with Alkynes Organic Letters. ,vol. 9, pp. 133- 136 ,(2007) , 10.1021/OL062732N
Mitsuru Miyasaka, Azusa Fukushima, Tetsuya Satoh, Koji Hirano, Masahiro Miura, Fluorescent diarylindoles by palladium-catalyzed direct and decarboxylative arylations of carboxyindoles. Chemistry: A European Journal. ,vol. 15, pp. 3674- 3677 ,(2009) , 10.1002/CHEM.200900098
Jihoon Shin, Stephen M. Jensen, Jinhun Ju, Sunwoo Lee, Zhigang Xue, Seok Kyun Noh, Chulsung Bae, Controlled Functionalization of Crystalline Polystyrenes via Activation of Aromatic C-H Bonds † Macromolecules. ,vol. 40, pp. 8600- 8608 ,(2007) , 10.1021/MA701984Q
Seth M. Cohen, Postsynthetic methods for the functionalization of metal-organic frameworks. Chemical Reviews. ,vol. 112, pp. 970- 1000 ,(2012) , 10.1021/CR200179U
Thomas Dröge, Andreas Notzon, Roland Fröhlich, Frank Glorius, Palladium-catalyzed C-H bond functionalization of a metal-organic framework (MOF): mild, selective, and efficient. Chemistry: A European Journal. ,vol. 17, pp. 11974- 11977 ,(2011) , 10.1002/CHEM.201101850
Joanna Wencel-Delord, Thomas Dröge, Fan Liu, Frank Glorius, Towards mild metal-catalyzed C–H bond activation Chemical Society Reviews. ,vol. 40, pp. 4740- 4761 ,(2011) , 10.1039/C1CS15083A
Satomi Nakazono, Yusuke Imazaki, Hyejin Yoo, Jaesung Yang, Takahiro Sasamori, Norihiro Tokitoh, Tassel Cédric, Hiroshi Kageyama, Dongho Kim, Hiroshi Shinokubo, Atsuhiro Osuka, None, Regioselective Ru‐Catalyzed Direct 2,5,8,11‐Alkylation of Perylene Bisimides Chemistry: A European Journal. ,vol. 15, pp. 7530- 7533 ,(2009) , 10.1002/CHEM.200901318
Bi-Jie Li, Zhang-Jie Shi, From C(sp2)–H to C(sp3)–H: systematic studies on transition metal-catalyzed oxidative C–C formation Chemical Society Reviews. ,vol. 41, pp. 5588- 5598 ,(2012) , 10.1039/C2CS35096C
Christina Meyer, Benedikt Neue, Dirk Schepmann, Shuichi Yanagisawa, Junichiro Yamaguchi, Ernst-Ulrich Würthwein, Kenichiro Itami, Bernhard Wünsch, Exploitation of an additional hydrophobic pocket of σ1 receptors: Late-stage diverse modifications of spirocyclic thiophenes by C–H bond functionalization Organic and Biomolecular Chemistry. ,vol. 9, pp. 8016- 8029 ,(2011) , 10.1039/C1OB06149F