Thimerosal-free preservatives for vaccines

作者: John P. Hennessey , Ralph J. Mancinelli , Assunta S. Ng

DOI:

关键词: ChromatographyThimerosalHigh-performance liquid chromatographyBenzyl alcoholPreservativeOrganic chemistryAntimicrobialChemistry

摘要: Novel combination of preservatives (methyl and propyl parabens, benzyl alcohol, 2-phenoxyethanol) were found to pass antimicrobial testing according USP, BP, EP. The new put into vaccines using L-histidine as a buffer keep p11 at 7O HPLC methods developed analyze these their degradation products.

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