作者: David B. Volkin , Henryk Mach , Li Shi
DOI:
关键词: Human papilloma virus 、 Pulmonary surfactant 、 Human papillomavirus vaccine 、 Chromatography 、 Salt (chemistry) 、 Materials science 、 Buffering agent 、 Stabilizer (chemistry)
摘要: New human papilloma virus (HPV) vaccine formulations exhibit enhanced long-term stability. Formulation components can include: virus-like particles (VLPs) absorbed onto aluminum, a salt, non-ionic surfactant, and buffer. Additional also contain polymeric polyanionic stabilizer salt either in the presence or absence buffering agents nonionic detergent.