Ataxic-hypotonic cerebral palsy in a cerebral palsy registry: Insights into a distinct subtype.

摘要: Objective To specifically report on ataxic-hypotonic cerebral palsy (CP) using registry data and to directly compare its features with other CP subtypes. Methods Data prenatal, perinatal, neonatal characteristics gross motor function (Gross Motor Function Classification System [GMFCS]) comorbidities in 35 children were extracted from the Canadian Cerebral Palsy Registry compared 1,804 patients subtypes of CP. Results Perinatal adversity was detected significantly more frequently (odds ratio [OR] 4.3, 95% confidence interval [CI] 1.5–11.7). The gestational age at birth higher (median 39.0 weeks vs 37.0 weeks, p = 0.027). Children displayed intrauterine growth restriction (OR 2.6, CI 1.0–6.8) congenital malformation 2.4, 1.2–4.8). MRI likely be either normal 3.8, 1.4–10.5) or show a 4.2, 1.5–11.9) There no significant difference terms GMFCS presence comorbidities, except for frequent communication impairment 1.5–11.6). Conclusions Our results suggest predominantly genetic prenatal etiology imply that diagnosis does not impart worse prognosis respect functional impairment. This study contributes toward better understanding as distinct nosologic entity within spectrum own pathogenesis, risk factors, clinical profile,