A case of Japanese pregnant woman who developed severe acute hepatitis E right after back from India
作者： Akishi Kourin , Kazuaki Inoue , Kazuaki Takahashi , Tsunamasa Watanabe , Masaya Yamada
DOI: 10.2957/KANZO.50.60
关键词: Acute hepatitis E 、 Surgery 、 Pediatrics 、 Medicine
摘要: E型肝炎ウイルス（HEV）はアジア・アフリカにおける流行性肝炎の重要な原因で，一般にはself-limitedな経過を取るが，妊婦では重症化しやすく致死率が高く胎児の合併症も多いとされる．今回我々は本邦で初めて妊娠中のHEV感染により急性肝炎重症型に陥った邦人妊婦例を経験した．本例はインドに長期滞在して帰国後2週間で発症し，入院時の血清よりgenotype 1のHEV RNA（JHN-Kan07R，AB447389）が検出された．抗ウイルス治療開始後速やかに肝機能は回復し，早産であったものの周産期の合併症もなく，母児共にその後は順調な経過をとった.
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