Etiology of fulminant hepatic failure: experience from a tertiary hospital in Bangladesh.

摘要: BACKGROUND Fulminant hepatic failure (FHF) is not uncommon in our clinical practice Bangladesh. There was a rise acute hepatitis E virus (HEV) Bangladesh after the 2004 floods. At that time, most of country under water for more than month, leading to sewage contamination supply. The aim this study investigate etiology FHF METHODS In retrospective study, 23 patients with who presented severe impairment hepatocellular function (i.e. encephalopathy, coagulopathy and jaundice) within 6 months onset symptoms were included. 17 men women, aged from 18 32 years. Four women pregnant. Patients tested markers common hepatotrophic viruses. A relevant history taken Patient Record Book Unit reviewed. RESULTS 56.52% (13/23) had HEV infection, all anti-HEV IgM-positive by ELISA. HBV infection detected 34.78% (8/23), whom positive either HBsAg or anti-HBs IgM 8.7% (2/23) intake alcohol and/or drugs. CONCLUSIONS Acute cause Sewage supply following floods contributes higher incidence infection. also important.