Failure of Passive Immune Transfer in Calves: A Meta-Analysis on the Consequences and Assessment of the Economic Impact

作者: Didier Raboisson , Pauline Trillat , Clélia Cahuzac

DOI: 10.1371/JOURNAL.PONE.0150452

关键词: Economic modelEconomic impact analysisTotal costMeta-analysisColostrumConfidence intervalPrediction intervalEstimationVeterinary medicineMedicineStatistics

摘要: Low colostrum intake at birth results in the failure of passive transfer (FPT) due to inadequate ingestion colostral immunoglobulins (Ig). FPT is associated with an increased risk mortality and decreased health longevity. Despite known management practices low FPT, it remains important issue field. Neither a quantitative analysis consequences nor assessment its total cost are available. To address this point, meta-analysis on adjusted associations between outcomes was first performed. Then, costs European systems were calculated using stochastic method values as input parameters. The risks (and 95% confidence intervals) for mortality, bovine respiratory disease, diarrhoea overall morbidity case 2.12 (1.43-3.13), 1.75 (1.50-2.03), 1.51 (1.05-2.17) 1.91 (1.63-2.24), respectively. mean prediction interval) per calf estimated be €60 (€10-109) €80 (€20-139) dairy beef, As result double-step method, proposed economic estimation constitutes estimate available FPT. presented way that facilitates their use field and, limited effort, combines each contributor increase applicability situations farm-advisors may face. present estimates also tool evaluate profitability measures aim improve prevention.

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