Frequency of stress lesions of the upper gastrointestinal tract in paediatric patients after cardiac surgery: effects of prophylaxis.

摘要: BACKGROUND--Stress lesions of the upper gastrointestinal tract are well recognised in adult patients intensive care. There no controlled studies incidence these and effects or side prophylactic treatment high risk paediatric patients. METHODS--79 care were studied prospectively after operation for congenital heart disease. All had at least one endoscopic examination. The first 36 not given medication: later 43 children treated randomly either with pirenzepine (n = 21) famotidine 22). Gastric tracheal secretions taken daily culture those medication. RESULTS--Severe inflammation ulceration was less common who medication (18% v 44%). Prophylactic did not, however, reduce total postoperative stress lesions: it shifted severity changes towards mild reduced ulcerations from 25% to 2%. None developed a pneumonia caused by an organism previously isolated stomach. CONCLUSIONS--The cardiac surgery resembles that Children should be prophylactically until they can fed mouth.