Vital functions for lethal caspases

作者: Sophie Launay , Olivier Hermine , Michaëla Fontenay , Guido Kroemer , Eric Solary

DOI: 10.1038/SJ.ONC.1208524

关键词: BiologyImmune systemInnate immune systemProteasesApoptosisProgrammed cell deathCell biologyCellular differentiationCaspaseIntrinsic apoptosis

摘要: Caspases are a family of cysteine proteases expressed as inactive zymogens in virtually all animal cells. These enzymes play a central role in most cell death pathways leading to …

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