Insights from Global Analyses of Long Noncoding RNAs in Breast Cancer.
作者： Andrew J. Warburton , David N. Boone
DOI: 10.1007/S40139-017-0122-1
关键词: Transcriptome 、 Immunology 、 Functional studies 、 Breast cancer 、 Computational biology 、 Cancer genome 、 Biology 、 Breast cancer cells
摘要: The goal of this review was to compare and contrast the results implications from several recent transcriptomic studies that analyzed expression long noncoding RNAs (lncRNAs) in breast cancer. How many lncRNAs are dysregulated cancer? Do contribute cancer etiology? Are viable biomarkers Transcriptomic profiling tissues, mostly Cancer Genome Atlas, identified thousands expressed alone can divide patients into molecular subtypes. Subsequent functional demonstrated these have important roles cell biology. Thousands be developed as for prognostic or therapeutic purposes. reviewed reports provide a roadmap guide discover with critical biological functions relating development progression.
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