Modelling hereditary diffuse gastric cancer initiation using transgenic mouse-derived gastric organoids and single-cell sequencing.

作者: David G Huntsman , Amal El-Naggar , Steve E Kalloger , Tanis D Godwin , Christine Chow

DOI: 10.1002/PATH.5675

关键词: CytokeratinGermlineSquamous DifferentiationBiologyHereditary diffuse gastric cancerCancer researchCancer syndromeSingle cell sequencingCDH1Cancer

摘要: … mouse stomach at single-cell resolution, we performed scRNA-seq … The mature mammalian stomach is composed of glands with … antral glands of the human stomach. While the mouse …

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