Obesity and gastric cancer.

摘要: Obesity is an important public health problem worldwide. It increases the risk of many chronic diseases such as diabetes and cardiovascular diseases. Meanwhile, obesity a major factor for several types cancer including gastric cancer. Possible mechanisms linking with may include associated gastro-oesophageal reflux, insulin resistance, altered levels adiponectin, leptin, ghrelin, abnormally increased blood level insulin-like growth (IGF). Helicobacter pylori (H. pylori) infection well-recognized peptic ulcer Recent studies have revealed prevalence H. in obese patients, providing another clue incidence population. If this connection can be confirmed animal models large cohort then eradicating together life style modification individuals help prevent development increasingly