Determination of 2,6-di-tert-butyl-hydroxytoluene and its transformation products in indoor dust and sediment by gas chromatography–mass spectrometry coupled with precolumn derivatization
作者： Ruirui Zhang , Chao Li , Yunzi Li , Xinyi Cui , Lena Q. Ma
DOI: 10.1016/J.SCITOTENV.2017.11.115
关键词: Mass spectrometry 、 Derivatization 、 Phenol 、 Hexane 、 Chemistry 、 Extraction (chemistry) 、 Gas chromatography–mass spectrometry 、 Dichloromethane 、 Environmental chemistry 、 Detection limit 、 Chromatography 、 Environmental engineering 、 Waste Management and Disposal 、 Pollution
摘要: We developed an analytical method to simultaneously determine 2,6-di-tert-butyl-hydroxytoluene (BHT) and its four transformation products in indoor dust sediment samples. BHT, 2,6-di-tert-butylcyclohexa-2,5-diene-1,4-dione (BHT-Q), 3,5-di-tert-butyl-4-hydroxybenzaldehyde (BHT-CHO) were measured by gas chromatography-mass spectrometry (GC-MS) after ultrasonic extraction with hexane/dichloromethane (1:3), while 2,6-di-tert-butyl-4-(hydroxymethyl) phenol (BHT-OH) 3,5-di-tert-butyl-4-hydroxybenzoic acid (BHT-COOH) derivatized using N, O-bis (trimethylsilyl) trifluoroacetamide before GC-MS analysis. The limits of detection (LODs) quantification (LOQs) the 0.02-0.34 0.08-1.14ngg-1. recoveries for BHT 71.1-118% relative standard deviations <10.6% at different spiking levels. was applied samples, showing that found all samples concentrations being 0.22-47.37μgg-1 0.09-6.93μgg-1 sediment. BHT-Q dominant product, followed BHT-CHO, BHT-OH, BHT-COOH. Different metabolite profiles indicated various pathways, making it necessary study their mechanism environmental behaviors future studies.
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