Incidences and Predictors of HIV Positivity among Infants who Born from HIV Positive Mother who Have Follow Up at Two Hospitals of Southern Ethiopia, 2014

作者: Tariku Tadele

DOI: 10.11648/J.SJPH.20140205.19

关键词: Acquired immunodeficiency syndrome (AIDS)Breast feedingTransmission (medicine)Proportional hazards modelHIV PositivityMedicineIncidence (epidemiology)PediatricsInfant mortalityPregnancy

摘要: Introduction: Despite a dramatic progress in improvements regarding infant mortality due to HIV/AIDS the past decades, is causing devastating impact on world’s children. Mother-to-child transmission (MTCT) by far largest source of HIV infection children under age 15, with 90% cases infected during pregnancy, birth, and major share after birth.Therefore, this study follows infants first test (Deoxyribonucleic acid (DNA) Polymerase Chain Reaction (PCR) testing) negative, until occurrences positivity predictors associated it two hospital Southern Ethiopia. Objective: The aim was assess incidence, Survival experiences among born from positive mothers Ethiopia, 2014. Methodology: Institution-Based Retrospective follow up conducted at Hawassa Referral Yirgalem General Hospital September 2000 August 2005 E.C. Data collected trained BSc nurses medical registration book 485 exposed . It entered EPI Info 3.5.1 exported SPSS version 20 for further analysis. Both Bivariate Multiple variable Cox regression analysis were identify predictors. P-value< 0.05 considered as level significance. Results: Among 457 participants included contributed 4249.4 Person Months up. Cumulative overall incidence rate 19(4.16%) 4.47/1000 PM (95% CI: 4.02-4.92) respectively. Mean free survival time difference between Exclusive breast feeding 20.2 (95 % CI, 19.6, 20.8)), mixed (17.5 15.5-19.5)) exclusive formula 16.8 16.3, 18.4) significant. Mixed (AHR: 8.23(1.98, 34.2)), ARV prophylaxis (yes) 0.19(95% 0.04-0.89)), Maternal HAART 0.16(95% .041, 0.59) SdNVP + AZT+ 3TC 0.113(95% 0.02, 0.61)) intervention independent infants. Conclusion: risk mother child high All should start PMTCT guideline better discourage prevent upcoming infection.

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