Overall Survival Is Impacted by Birthplace and Not Extent of Surgery in Asian Americans with Resectable Gastric Cancer

摘要: Survival from gastric cancer in the USA still lags behind Asia. Genetic, environmental, and tumor biology differences, along with extent of surgery have been implicated. Our aim was to evaluate survival outcomes Asian-American patients undergoing surgical resection by comparing place birth clinicopathologic characteristics (including evaluation 15 lymph nodes).The Surveillance, Epidemiology, End Results database queried identify treated surgically for curative intent (2000–2010). US-born versus foreign-born were analyzed survival. Secondary comparison made non-Asian patients. Stage IV non-surgical excluded. Of 10,089 identified, 1467 Asian: 271 born USA, 1196 outside USA. Median 32 months non-Asians 29 Asians 61 Asian immigrants (p < 0.001). On multivariable analysis overall patients, only US birthplace, older age, higher stage yielded a significantly poorer outcome. worse prognosis if Anatomic differences do not explain this disparity; environmental factors may be responsible.