Voice Outcomes Following Radiation Versus Laser Microsurgery for T1 Glottic Carcinoma Systematic Review and Meta-analysis

作者: Matthew T. Greulich , Noah P. Parker , Philip Lee , Albert L. Merati , Stephanie Misono

DOI: 10.1177/0194599815577103

关键词: Transoral laser microsurgeryVoice Handicap IndexMeta-analysisGlottic Squamous Cell CarcinomaSurgeryMedicineGlottisGlottic cancerMedical physicsQuality of lifeRadiation therapy

摘要: ObjectiveSystematic review of literature on patient-reported voice handicap following T1 glottic squamous cell carcinoma treatment using transoral laser microsurgery or radiation therapy.Data SourcesPubMed, Web Science, and Scopus (1997-2013).Review MethodsThese data sources were searched for papers reporting Voice Handicap Index (VHI) after early carcinoma. Review reference cross-checking performed a priori selection criteria. Study abstracted publication quality categorized independently by 2 authors. Corresponding authors contacted to maximize analysis. Meta-analysis was only with studies that included both modalities, reduce heterogeneity rigor; random effects modeling used pool results.ResultsEighteen publications identified reported VHI surgery radiotherapy No randomized. When multiple T-stages syste...

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