Peptide that inhibits janus kinase
作者： Emmanuelle Fantino , Andrew Frederick Wilks , Julie Atkin
DOI:
关键词: Janus kinase 、 PSL 、 Biochemistry 、 Peptide 、 Biology 、 JAK activity 、 Kinase
摘要: The present invention provides a method of selecting or designing compound for the ability to regulate JAK activity. comprises assessing modulate interaction pseudo-substrate loop (PSL) with kinase like domain (KLD) JAK. In addition compounds which inhibit and methods treatment JAK-associated disease states.
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