Recurrent Cutaneous Herpes Simplex in Hairless Mice

摘要: Passively immunized hairless mice were inoculated cutaneously with herpes simplex virus. Thirty-nine days later, when the primary cutaneous lesions had completely healed, treated subcutaneously prednisone. Within 12 to 30 after starting prednisone treatment, herpesvirus was recovered by skin swabs from of 71 (17%) mice. This new model has potential application for understanding and treating recurrent infections.