Cancer in the contralateral breast after radiotherapy for breast cancer.
作者：
DOI: 10.1056/NEJM199208063270614
关键词: Mammary gland 、 Case-control study 、 Breast cancer 、 Risk factor 、 Radiation therapy 、 Cohort 、 Medical record 、 Medicine 、 Internal medicine 、 Cancer 、 Oncology
摘要: Abstract Background. Patients with breast cancer have a threefold increase in the risk that second will develop. Radiation treatment for initial can result moderately high doses to contralateral breast, possibly contributing this heightened risk. Methods. We conducted case–control study cohort of 41,109 women diagnosed between 1935 and 1982 Connecticut. reviewed medical records 655 whom developed five or more years after tumor compared their radiation exposure 1189 matched controls from who did not cancer. The dose was estimated original radiotherapy records. Among exposed women, average 2.82 Gy (maximum, 7.10). Results. Overall, 23 percent had 20 received (re...
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