Regulation of SMRT and N-CoR Corepressor Function
作者： M. L. Privalsky
DOI: 10.1007/978-3-662-10595-5_6
关键词: Corepressor 、 Mediator 、 Transcriptional regulation 、 Nuclear receptor 、 Cell biology 、 Biology 、 Genetics 、 Nuclear receptor co-repressor 2 、 Nuclear receptor co-repressor 1 、 Psychological repression 、 Thyroid hormone receptor
摘要: This review will describe how the functions of transcriptional corepressors are regulated in cells. I focus primarily on SMRT (Silencing Mediator Retinoic acid and Thyroid hormone receptors) N-CoR (Nuclear receptor Co-Repressor) complexes that mediate repression by nuclear receptors (Chen Evans 1995; Horlein et al. Sande Privalsky 1996). Given these same also participate a variety other factors, including PLZF, BCL-6, Myo D, CBF-1/RBP-Jk, ETO, this touch aspects regulation non-receptor transcription factors (Dhordain 1997; Hong Gelmetti 1998; Grignani Guidez He Kao Lin Lutterbach Wong 1998a; Bailey 1999).
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