Serologic response to rabies pre-exposure vaccination in persons with potential occupational exposure in Singapore

摘要: Summary Sixty-six animal workers received primary rabies vaccination with purified Vero cell vaccine (PVRV, Verorab™). One year later, 26 (39%) demonstrated antibody titers below the recommended minimum of 0.5IU/ml, and required a booster. All 15 separate group reporting at least one booster had above 0.5IU/ml 1 demonstrating long-term boostable immunity. Rabies should be checked after in persons high risk frequent exposure. If access to serological surveillance is unavailable, such high-risk individuals receive vaccination.