Bioactive Terpenoids and Flavonoids from Ginkgo Biloba Extract Induce the Expression of Hepatic Drug-Metabolizing Enzymes Through Pregnane X Receptor, Constitutive Androstane Receptor, and Aryl hydrocarbon Receptor-Mediated Pathways

作者: Linhao Li , Joseph D. Stanton , Antonia H. Tolson , Yuan Luo , Hongbing Wang

DOI: 10.1007/S11095-008-9788-8

关键词: GinkgoalesCytochrome P450BiochemistryBiologyPregnane X receptorGinkgo bilobaAryl Hydrocarbon HydroxylasesConstitutive androstane receptorDownregulation and upregulationPharmacologyAryl hydrocarbon receptor

摘要: Purpose The objective of the current study is to investigate the hypothesis that bioactive terpenoids and flavonoids of Ginkgo biloba extract (GBE) induce human hepatic drug …

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