Increased topoisomerase IIα expression in colorectal cancer is associated with advanced disease and chemotherapeutic resistance via inhibition of apoptosis

作者: Alan Coss , Miriam Tosetto , Edward J. Fox , Beata Sapetto-Rebow , Sheeona Gorman

DOI: 10.1016/J.CANLET.2008.11.018

关键词: EtoposideCell cycleFluorescence in situ hybridizationMolecular biologyProliferation indexIrinotecanChromosome instabilityChemotherapyApoptosisBiology

摘要: … color planes; Cy3, Cy5, and DAPI. Following subtraction of … Fluorescence mounting medium (30 μl) containing DAPI was … at 385 nm for DAPI, 488 nm for FITC and 543 for TRITC. Z-…

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