Theoretical models for heterogeneity of base composition in DNA
作者： R.A. Elton
DOI: 10.1016/0022-5193(74)90129-5
关键词: C content 、 Gene 、 Biology 、 Theoretical models 、 Sequence (medicine) 、 Genetics 、 DNA 、 Base (exponentiation) 、 Evolutionary biology 、 Molecular size 、 Composition (combinatorics)
摘要: Abstract Data on DNA base composition heterogeneity and molecular size, mainly from bacteria, are compiled the literature. A series of theoretical models increasing complexity is put forward, it concluded that data support a model in which consists sequence “segments” with different underlying compositions. Estimates mean segment length variance G + C content made. The possibility excess above random results variation coded proteins considered rejected. It probably caused by variations relative use synonymous codons genes.
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