Human natural killer cell subsets and acute exercise: a brief review.

摘要: Natural killer (NK) cells are the most responsive immune cell to acute exercise. This sensitivity physiological stress combined with their role in innate defences suggests that these may be a link between regular physical activity and overall health status. NK heterogeneous population consisting of at least two distinct subsets based on expression intensity CD56. CD56(bright) CD56(dim) exhibit different phenotypical functional characteristics. In this review, we examine effects exercise subsets, special reference potential implications findings. The available evidence differential mobilization response exercise; less than counterparts. During post-exercise recovery period (up 1 h), ratio CD56(bright):CD56(dim) favours subset. significance findings is discussed context normal adaptation We also discuss certain clinical conditions (e.g., multiple sclerosis) as an adjunct therapy mobilize Further investigation into biology should prove fruitful area for years come.