Radical cystectomy and the implications of comorbidity.

作者: Roman Mayr , Hans-Martin Fritsche , Alexander Pycha , Armin Pycha

DOI: 10.1586/14737140.2014.868775

关键词: RefractoryDissectionOncologySurgeryLymph nodeInternal medicineComorbidityGold standardCystectomyIn patientMedicineDisease

摘要: Radical cystectomy (RC) with pelvic lymph node dissection constitutes the gold standard treatment for muscle-invasive urothelial carcinoma of bladder and high-risk nonmuscle-invasive disease refractory to instillation therapy. Although RC is performed curative intent, overall 5-year survival has been reported be as low 62% in current literature. Various clinicopathological parameters determine post-RC outcome, but besides these, role comorbidity gained increasing attention. In clinical practice, information quantified using various evaluated indices. this paper, we discuss most recent data on performance indices assessed patients undergoing highlight their implications.

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