The association of preoperative serum albumin level and American Society of Anesthesiologists (ASA) score on early complications and survival of patients undergoing radical cystectomy for urothelial bladder cancer

作者: Hooman Djaladat , Harman Maxim Bruins , Gus Miranda , Jie Cai , Eila C. Skinner

DOI: 10.1111/BJU.12240

关键词: CystectomyBladder cancerAmerican society of anesthesiologistsHazard ratioUrologySerum albumin levelSerum albuminSurgeryComplicationMedicineConfidence interval

摘要: Objective To evaluate the impact of preoperative American Society Anesthesiologists (ASA) score and serum albumin level on complications, recurrences survival rates patients who underwent radical cystectomy (RC) for urothelial bladder cancer (UBC). Patients Methods In all, 1964 RC UBC at our institution between 1971 2008. Preoperative ASA were available in 1471 1140 patients, respectively. A complication was defined as any surgery related/unrelated event leading to lengthening hospital stay or re-admission. Endpoints 90-day (90dC) rate, recurrence-free (RFS) overall (OS). Results The median (range) follow-up 12.4 (0.2–27.3) years. In 197 (13.4%) had a low (<3.5 g/dL) 740 (64.8%) high (3 4). Low associated with higher 90dC rate (42% vs 34%, P = 0.03 40% 28%, < 0.001, respectively). On multiple logistic regression analysis, remained independently increased (hazard ratio [HR] 1.52, 0.005) decreased OS (HR 1.45, 95% confidence interval [CI] 1.13–1.86). A also RFS 1.68, CI 1.16–2.43) 1.93, 1.43–2.63). Conclusion A recurrence after RC. A OS. These parameters potentially could be used prognosticators RC.

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