Changing Trends in Prevalence and Antibiotics Resistance of Uropathogens in Patients Attending the Gondar University Hospital, Northwest Ethiopia

摘要: Background. In most hospitals of developing countries, urinary tract infections are treated empirically because lack culture facilities. This leads to emergence multiresistant uropathogens. Culturing and drug susceptibility testing essential guide therapy. Objectives. To assess changing prevalence resistance pattern uropathogens commonly used antibiotics in a two-year study period. Methods. Urine specimens were collected cultured. Uropathogens identified by standard methods tested for resistance. Data analyzed using SPSS version 16 statistical sofware. P value < 0.05 was considered statistically significant. Results. The commonest isolates both the previous present studies E. coli, Klebsiella, CoNS, S. aureus, Proteus, Citrobacter species. Previous Enterobacteriaceae 100% sensitive ciprofloxacin, whereas developed 31% 60% it. less resistant gentamycin than ones. Multiresistance predominant Conclusion. coli two periods. Present more Some increasingly resistant. Ciprofloxacin gentamicin have been recommended empiric treatment infections.