Bacterial profile and drug susceptibility pattern of urinary tract infection in pregnant women at Tikur Anbessa Specialized Hospital Addis Ababa, Ethiopia.

摘要: BACKGROUND Urinary tract infection (UTI) is a common complication of pregnancy. It may be symptomatic or asymptomatic. OBJECTIVES The aim this cross sectional study was to identify bacterial agents and their antibiotic susceptibility pattern isolated from pregnant women with UTI attending antenatal clinic Tikur Anbessa Specialized Hospital (TASH). METHODS Four hundred fourteen asymptomatic (n = 369) 45) were investigated for urinary January March 2005. RESULTS age range both groups 18 44 years. Bacteriological screening mid-stream urine specimens revealed that 39/369 (10.6%) 9/45 (20%) had significant bacteriuria in group, respectively (p 0.10). overall prevalence 48/414 (11.6%). pathogens predominantly E. coil (44%), followed by S. aureus (20%), coagulase-negative staphylococci (16%), K. pneumoniae (8%). Others found small number included P. mirabilis, aeruginosa, Enterococcus spp. non-Group A-beta hemolytic Streptococcus, accounted 2% each. gram positive negative bacteria 40% 60% respectively. gram-negative showed most the isolates (> 65% strains) sensitive amoxicillin-clavulanic acid (70%), chloramphenicol (83.3%), gentamicin (93.3%), kanamycin nitrofurantoin (87.7%) trimethoprim-sulphamethoxazole (73.3%). Among gram-positives, more than (100%), cephalothin (95%), erythromycin (80%), (85%), methicillin (100%) (65%). Generally, acid, chloramphenicol, gentamicin, effective at least 70% isolates. Multiple drug resistance (resistance two drugs) observed 74% CONCLUSION Significant women. Periodic studies are recommended confirm findings also monitor any changes patterns uropathogens causing