Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.

作者: Aparna Raval , Stephan M. Tanner , John C. Byrd , Elizabeth B. Angerman , James D. Perko

DOI: 10.1016/J.CELL.2007.03.043

关键词: AlleleCancer researchEpigeneticsChronic lymphocytic leukemiaGermlineDNA methylationPhenotypeBCL9BiologyGermline mutation

摘要: The heritability of B cell chronic lymphocytic leukemia (CLL) is relatively high; however, no predisposing mutation has been convincingly identified. We show that loss or reduced …

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