Variability in response to nicotine in the LSxSS RI strains: potential role of polymorphisms in α4 and α6 nicotinic receptor genes

作者: Theresa Tritto , Jerry A. Stitzel , Michael J. Marks , Elena Romm , Allan C. Collins

DOI: 10.1097/00008571-200204000-00004

关键词: GeneHeart rateReceptorRespirationRestriction fragment length polymorphismPolymorphism (computer science)GeneticsNicotineNicotinic agonistBiology

摘要: Several studies have shown that genetic factors influence the effects of nicotine on respiration, acoustic startle, Y-maze crosses and rears, heart rate body temperature in mouse. Recently, we identified restriction fragment length polymorphisms (RFLPs) associated with α4 (Chrna4) α6

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