3D-printed radiopaque polymer composites for the in situ monitoring of biodegradable medical implants
作者： Chia-Teng Chang , Hsin-Ting Chen , Samuel Pratama Girsang , Yu-Min Chen , Dehui Wan
DOI: 10.1016/J.APMT.2020.100771
关键词: Materials science 、 Polymer composites 、 Bismuth subcarbonate 、 Bismuth oxychloride 、 Biomedical engineering 、 Radiodensity 、 Barium sulfate 、 In situ 、 Polymer 、 Acrylate
摘要: Abstract The development of biodegradable medical implants that are observable through rapid and non-invasive imaging techniques is crucial toward the treatments many illnesses. However, tracking devices in post-implantations remains problematic, due to intrinsic radio-transparency polymeric device. In this study, we developed a 3D-printable radiopaque polymer with tunable degradation rates mechanical properties, can be characterized X-ray computed tomography (CT). Three radiopacifiers were introduced poly(glycerol sebacate) acrylate (PGSA), including barium sulfate, bismuth subcarbonate, oxychloride, resulted radiopacities equivalent intensities commercial BIOTEQⓇ pigtail drainage catheters. changes properties varying concentration studied, oxychloride embedded PGSA (PGSA-BiOCl) was chosen for vitro over 30 days. linear correlation between mass loss decrease radiopacity PGSA-BiOCl time indicates possible application monitoring degrading implants, contrast similar PCL products. Through digital light processing additive manufacturing (DLP-AM), proven equally visible under radiological when comparing
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