Growth inhibition of human fibroblasts in vitro.
作者： Alvaro Macieira-Coelho
DOI: 10.1007/978-3-642-72149-6_11
关键词: In vivo 、 Senescence 、 Growth inhibition 、 Contact inhibition 、 Homeostasis 、 Biology 、 Cell 、 In vitro 、 Cell biology 、 Population
摘要: Growth arrest of human fibroblasts maintained in vitro occurs when the density increases and cells become confluent; this is so-called contact inhibition growth characteristic all normal cells. also at end cell population’s proliferative life span, a state that has been erroneously called senescence but which irrelevant for aging organism since terminal present tissues vivo amounts unrelated to age donor (Macieira-Coelho 1995). This supposed be differentiated (Martin et al. 1974), although its putative role homeostasis not identified so far. An increased number was found under pathological conditions
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