Factors Associated with Awareness of Infection Status among Chronic Hepatitis B and C Carriers in Korea

作者: Aesun Shin , Eo Rin Cho , Jeongseon Kim , Joohon Sung , Kyung Woo Park

DOI: 10.1158/1055-9965.EPI-08-1228

关键词: Hepatitis BPopulation studyDiseaseHepatitisInternal medicineHepatitis CCohortFamily historyOdds ratioImmunologyMedicine

摘要: Hepatitis B (HBV) and hepatitis C (HCV) viral infections are the most important risk factors for hepatocellular carcinoma (HCC), which is responsible 17.5% of cancer deaths in Korea. The objectives this study were to identify demographic characteristics that may affect carriers' awareness their infection status, assess whether health-related behaviors differed by infection. Among 18,636 persons who recruited from a screenee cohort, 904 HBV carriers 146 HCV carriers. carriers, 74.2% aware status. Higher education (odds ratio, 1.8; college versus middle school or less), family history liver disease, marriage associated with Participants carrier status more likely be former smokers drinkers than those not Only 34.9% No related among However, 9.2; 95% confidence interval, 1.8-47.2). In conclusion, two thirds one fourth population was significantly other behaviors, such as alcohol consumption cigarette smoking.

参考文章(15)
Li-Yu Wang, San-Lin You, Sheng-Nan Lu, Hsi-Chang Ho, Mei-Hui Wu, Chien-An Sun, Hwai-I Yang, Chien-Jen Chen, Risk of hepatocellular carcinoma and habits of alcohol drinking, betel quid chewing and cigarette smoking: a cohort of 2416 HBsAg-seropositive and 9421 HBsAg-seronegative male residents in Taiwan Cancer Causes & Control. ,vol. 14, pp. 241- 250 ,(2003) , 10.1023/A:1023636619477
Timothy R. Morgan, Sarathy Mandayam, M. Mazen Jamal, Alcohol and hepatocellular carcinoma. Gastroenterology. ,vol. 127, pp. 87- 96 ,(2004) , 10.1053/J.GASTRO.2004.09.020
Hai-Rim Shin, Epidemiology of Hepatitis C Virus in Korea Intervirology. ,vol. 49, pp. 18- 22 ,(2006) , 10.1159/000087258
Margaret R. Spitz, Jean Nicolas Vauthey, Eddie Abdalla, Adel S. El-Deeb, Nga T. Nguyen, Donghui Li, Melanie B. Thomas, Lee M. Ellis, Katrina Y. Glover, Richard D. Lozano, Manal M. Hassan, James L. Abbruzzese, Steven A. Curley, Thomas D. Brown, Wenyaw Chan, Yehuda Z. Patt, Ahmed Kaseb, Effect of different types of smoking and synergism with hepatitis C virus on risk of hepatocellular carcinoma in American men and women: case-control study. International Journal of Cancer. ,vol. 123, pp. 1883- 1891 ,(2008) , 10.1002/IJC.23730
Lawrence Serfaty, Hugues Aumaître, Olivier Chazouillères, Anne-Marie Bonnand, Olivier Rosmorduc, Renée E. Poupon, Raoul Poupon, Determinants of outcome of compensated hepatitis C virus-related cirrhosis Hepatology. ,vol. 27, pp. 1435- 1440 ,(1998) , 10.1002/HEP.510270535
Hai-Rim Shin, Soon Young Hwang, Chung-Mo Nam, The Prevalence of Hepatitis C Virus Infection in Korea: Pooled Analysis Journal of Korean Medical Science. ,vol. 20, pp. 985- 988 ,(2005) , 10.3346/JKMS.2005.20.6.985
Giovanna Fattovich, Giuliano Giustina, Solko W. Schalm, Stephanos Hadziyannis, Josè Sanchez-Tapias, Piero Almasio, Erik Christensen, Kim Krogsgaard, Francoise Degos, Miguel Carneiro De Moura, Antonio Solinas, Franco Noventa, Giuseppe Realdi, Occurrence of hepatocellular carcinoma and decompensation in Western European patients with cirrhosis type B Hepatology. ,vol. 21, pp. 77- 82 ,(1995) , 10.1002/HEP.1840210114
Silvia Franceschi, Maurizio Montella, Jerry Polesel, Carlo La Vecchia, Anna Crispo, Luigino Dal Maso, Pietro Casarin, Francesco Izzo, Luigi G. Tommasi, Isabelle Chemin, Christian Trépo, Marina Crovatto, Renato Talamini, Hepatitis viruses, alcohol, and tobacco in the etiology of hepatocellular carcinoma in Italy. Cancer Epidemiology, Biomarkers & Prevention. ,vol. 15, pp. 683- 689 ,(2006) , 10.1158/1055-9965.EPI-05-0702
Francesco Donato, A Tagger, Umberto Gelatti, Giovanni Parrinello, P Boffetta, A Albertini, A Decarli, P Trevisi, ML Ribero, C Martelli, Stefano Porru, Giuseppe Nardi, Alcohol and Hepatocellular Carcinoma: The Effect of Lifetime Intake and Hepatitis Virus Infections in Men and Women American Journal of Epidemiology. ,vol. 155, pp. 323- 331 ,(2002) , 10.1093/AJE/155.4.323