Effects of Magnolol and Honokiol on Adhesion, Yeast-Hyphal Transition, and Formation of Biofilm by Candida albicans
作者： Lingmei Sun , Kai Liao , Dayong Wang
DOI: 10.1371/JOURNAL.PONE.0117695
关键词: Corpus albicans 、 Virulence 、 Adhesion 、 Magnolol 、 Candida albicans 、 Biology 、 Hyphal growth 、 Microbiology 、 Biofilm 、 Honokiol
摘要: Background The first step in infection by Candida albicans is adhesion to host cells or implanted medical devices and this followed hyphal growth biofilm formation. Yeast-to-hyphal transition has long been identified as a key factor fungal virulence. Following formation, C. usually less sensitive insensitive antifungals. Therefore, development of new antifungals with inhibitory action on adhesion, yeast-hyphal formation very necessary.
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