Deep sequencing of patient genomes for disease diagnosis: when will it become routine?
作者： Stephen F Kingsmore , Carol J Saunders , None
DOI: 10.1126/SCITRANSLMED.3002695
关键词: Computational biology 、 Disease 、 DNA sequencing 、 Bioinformatics 、 Clinical diagnosis 、 Genome 、 Biology 、 Translational medicine 、 Deep sequencing 、 Personal genomics
摘要: Next-generation sequencing technologies have greatly lowered the cost of whole-genome (WGS) and related approaches. Thus, comprehensive for diagnostic purposes may clear this financial hurdle in near future. The report by Bainbridge colleagues issue Science Translational Medicine illustrates power WGS. In Perspective, we discuss whether how genome might become routine clinical diagnosis.
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