Inter-Organ and -Tissue Communication via Secreted Proteins in Humans

摘要: Adipose tissue is now recognized as an important source of bioactive molecules, so-called adipokines. These adipokines, in turn, modulate hormone action, nutrient metabolism, inflammation, and energy balance. Thus, adipokines are part a complex biologic system that allows adipose to communicate with other tissue/organ systems, including skeletal muscle, liver, brain. Adiponectin abundant plasma adipokine secreted primarily from adipocytes. Unlike concentrations adiponectin decreased obesity metabolic syndrome. Therefore, impaired regulation secretion signaling appears be the development maintenance obesity-related complications. In this chapter, action will examined, example how organ-specific linked homeostasis humans.