Association between erectile dysfunction and echocardiographic variables of ventricular hypertrophy and diastolic function in hypertensive patients with type 2 diabetes mellitus: a cross-sectional study.
作者： Mateus Dornelles Severo , Liana Farias Leiria , Priscila dos Santos Ledur , Alexandre Dalpiaz Becker , Fernanda Musa Aguiar
关键词: Diastolic function 、 Diabetes mellitus 、 Ventricular hypertrophy 、 Cross-sectional study 、 Internal medicine 、 Erectile dysfunction 、 Type 2 Diabetes Mellitus 、 Medicine 、 Cardiology
摘要: Background This study was conducted among individuals with diabetes and hypertension in order to assess the prevalence of erectile dysfunction (ED) association between ED cardiovascular risk variables such as echocardiographic changes. Methods We evaluated 114 men type 2 mellitus hypertension. assessed by International Index Erectile Function (IIEF-5) score. Clinical laboratory were evaluated, including C-reactive protein (CRP), ambulatory blood pressure monitoring (ABPM), ankle brachial index (ABI) transthoracic echocardiography. Comparisons patients (IIEF-5 < 22) without ≥ performed. Results Patients 56.8 ± 5.7 years-old, systolic diastolic 150.7 19.5 mmHg 85.4 11.4 mmHg, respectively, HbA1c 8.0 1.7%. The majority (74.6%) had ED. Levels CRP, ABPM values ABI similar Echocardiography related cardiac chamber diameters, left ventricular hypertrophy function groups, except there a slight lower ejection fraction (64.9 7.3 vs 68.1 3.9%, P = 0.004). Conclusions In high hypertensive diabetes, is highly prevalent expected, but its presence associated neither variables, nor other factors. 摘要 背景：这项研究是在同时患有糖尿病与高血压的患者中进行的，目的是评估勃起功能障碍（erectile dysfunction，ED）的患病率以及ED与心血管风险变量例如超声心动图变化之间的关系。 方法：我们对114名同时患有2型糖尿病与高血压的男性患者进行了评估。使用国际勃起功能指数（International Function，IIEF-5）评分来评估ED。还评估了其他临床与实验室变量，包括C-反应蛋白（C-reactive protein，CRP）、动态血压监测（ambulatory monitoring，ABPM）、踝臂指数（ankle index，ABI）以及经胸壁超声心动图。在有ED（IIEF-5 22）与无ED（IIEF-5 22）的患者之间进行比较。 结果：患者的年龄为56.8 5.7岁，收缩期与舒张期血压分别为150.7 19.5 mmHg与85.4 11.4 mmHg，HbA1c为8.0 1.7%。大部分（74.6%）患者有ED。有和无ED的男性患者的CRP水平、ABPM值以及ABI都相似。除了有ED的男性患者的左心室射血分数有轻微下降以外（分别为64.9 7.3与68.1 3.9%，P=0.004），两组之间与心腔直径、左心室肥厚以及舒张功能相关的超声心动图变量相似。 结论：在同时患有糖尿病与高血压的高心血管风险患者中，就像我们预期的那样ED患病率非常高，但是ED的存在与超声心动图变量或者其他的心血管危险因素之间都没有相关性。
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