Methods and/or Use of Oligonucleotide Conjugates for Suppressing Background Due to Cross-Hybridization

作者: Xinfang Zhao , Amy Catherine Flor , Stephen J. Kron , David A. Schwartz , Jimmy Williams

DOI:

关键词: ConjugateSequence (biology)Cross hybridizationCombinatorial chemistryConjugated systemMoietyBiologyOligonucleotideMolecular biologyMolecular probe

摘要: The present disclosure is directed to methods and/or uses of oligonucleotide conjugates for assays and detections related systems kits suppressing background due cross-hybridization. Certain are a method detecting one or more biological targets sample in detection assay, comprising: providing molecular probe, comprising binding moiety an sequence, targets; the with moiety; detectable component sample, wherein comprises signal generating conjugated sequence complementary probe; hydridizing target-bound probe component; generated from hydridized component. Various other embodiments, applications etc. disclosed herein.

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