Relationship between radioadaptive response and individual radiosensitivity to low doses of gamma radiation: an extended study of chromosome damage in blood lymphocytes of three donors.

作者: Olga Komova , Eugene Krasavin , Elena Nasonova , Larisa Mel’nikova , Nina Shmakova

DOI: 10.1080/09553002.2018.1399226

关键词: ChromosomeBiologyRadiosensitivityImmunologyγ irradiationCancer researchRadiationLow dose

摘要: Purpose: Our study aimed at evaluating: 1) whether well-established variability in radioadaptive response (AR) various donor blood lymphocytes might be attributed to inter-individual differences...

参考文章(75)
Seán P. Barry, Paul A. Townsend, Richard A. Knight, Tiziano M. Scarabelli, David S. Latchman, Anastasis Stephanou, STAT3 modulates the DNA damage response pathway. International Journal of Experimental Pathology. ,vol. 91, pp. 506- 514 ,(2010) , 10.1111/J.1365-2613.2010.00734.X
Q. Han, N. Bagheri, E. M. Bradshaw, D. A. Hafler, D. A. Lauffenburger, J. C. Love, Polyfunctional responses by human T cells result from sequential release of cytokines Proceedings of the National Academy of Sciences of the United States of America. ,vol. 109, pp. 1607- 1612 ,(2012) , 10.1073/PNAS.1117194109
S. I. Zaichkina, O. M. Rozanova, G. F. Aptikaeva, A. Ch. Achmadieva, D. Y. Klokov, Low Doses of Gamma-Radiation Induce Nonlinear Dose Responses in Mammalian and Plant Cells Nonlinearity in Biology, Toxicology, and Medicine. ,vol. 2, pp. 213- 221 ,(2004) , 10.1080/15401420490519861
K. R. Atkuri, L. A. Herzenberg, A.-K. Niemi, T. Cowan, L. A. Herzenberg, Importance of culturing primary lymphocytes at physiological oxygen levels. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 104, pp. 4547- 4552 ,(2007) , 10.1073/PNAS.0611732104
J. H. Levine, Y. Lin, M. B. Elowitz, Functional Roles of Pulsing in Genetic Circuits Science. ,vol. 342, pp. 1193- 1200 ,(2013) , 10.1126/SCIENCE.1239999
Soile Tapio, Vesna Jacob, Radioadaptive response revisited. Radiation and Environmental Biophysics. ,vol. 46, pp. 1- 12 ,(2007) , 10.1007/S00411-006-0078-8
J. Hain, R. Jaussi, W. Burkart, Lack of adaptive response to low doses of ionizing radiation in human lymphocytes from five different donors Mutation Research Letters. ,vol. 283, pp. 137- 144 ,(1992) , 10.1016/0165-7992(92)90146-9
M.J. Loos, A.T. Natarajan, K. Sankaranarayanan, A.v. Duyn, Adaptive response of human lymphocytes to low-level radiation from radioisotopes or X-rays. Mutation Research. ,vol. 211, pp. 7- 12 ,(1989) , 10.1016/0027-5107(89)90101-2
Rebecca Elston, Gareth J. Inman, Crosstalk between p53 and TGF-β Signalling Journal of Signal Transduction. ,vol. 2012, pp. 294097- 294097 ,(2012) , 10.1155/2012/294097