A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively

摘要: Abstract Background Postoperative pancreatic fistula (POPF) is regarded as the most serious complication of surgery. The preoperative risk stratification patients by simple means interest in perioperative clinical management. Methods Based on prospective data, we performed a factor analysis for POPF after pancreatoduodenectomy 62 operated between 2006 and 2008 with special focus parameters that might serve to predict POPF. A predictive score was developed validated an independent second dataset 279 2001 2010. Results Several pre- intraoperative factors, well underlying pathology, showed significant univariate correlation rate Multivariate (binary logistic regression) disclosed soft texture (odds ratio [OR] 10.80, 95% confidence interval [CI] 1.80–62.20) history weight loss (OR 0.15, CI 0.04–0.66) be only factors influencing rate. subjective assessment hardness surgeon correlated highly objective fibrosis pathologist ( r  = −0.68, P Conclusions Preoperative regarding feasible. Pancreatic texture, evaluated intraoperatively surgeon, strongest single findings study may have important implications patient care, choice anastomotic techniques.