A case of NUT midline carcinoma with no HPV infection, slight EWSR1 rearrangement and strong expression of EGFR.
作者： Elvio De Fiori , Massimo Barberis , Fausto Maffini , Michela Manzotti , Eleonora Pisa
DOI: 10.1700/1361.15114
关键词: Oncology 、 Carcinoma 、 NUT midline carcinoma 、 Internal medicine 、 Fusion gene 、 HPV infection 、 Regulation of gene expression 、 Immunohistochemistry 、 Neoplasm 、 Gene rearrangement 、 Medicine
摘要: NUT midline carcinoma (NMC) is a rare neoplasm with poor prognosis and involving mostly young patients. Here we describe classic NMC BRD4-NUT fusion gene in middle-aged woman. We also analyzed some biological features that could potentially influence its clinical behavior such as HPV infection, EWSR1 rearrangement, the status of EGFR gene.
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