Regulation of DNA Replication by the Retinoblastoma Tumor Suppressor Protein
作者： Erik S. Knudsen , Steven P. Angus
关键词: Retinoblastoma-like protein 1 、 Origin recognition complex 、 Eukaryotic DNA replication 、 DNA replication 、 DNA replication factor CDT1 、 Biology 、 E2F1 、 Cancer research 、 Retinoblastoma protein 、 Replication Initiation
摘要: RB is a critical tumor suppressor targeted at high frequency in human cancers. As part of its mode action participates the regulation DNA replication. In absence functional aberrant replication cycles occur and genotoxic stresses are compromised for inhibiting Varied mechanisms through which inhibits S-phase have been described provide evidence temporally regulated stalling initiation followed by stable replicative exit.
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K. Münger, B.A. Werness, N. Dyson, W.C. Phelps, E. Harlow, P.M. Howley, Complex formation of human papillomavirus E7 proteins with the retinoblastoma tumor suppressor gene product. The EMBO Journal. ,vol. 8, pp. 4099- 4105 ,(1989) , 10.1002/J.1460-2075.1989.TB08594.X
Erick J. Morris, Nicholas J. Dyson, Retinoblastoma protein partners Advances in Cancer Research. ,vol. 82, pp. 1- 54 ,(2001) , 10.1016/S0065-230X(01)82001-7
Domenico Maiorano, Jacques Moreau, Marcel Méchali, XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis Nature. ,vol. 404, pp. 622- 625 ,(2000) , 10.1038/35007104
Romina Mossi, Ulrich Hubscher, Clamping down on clamps and clamp loaders--the eukaryotic replication factor C. FEBS Journal. ,vol. 254, pp. 209- 216 ,(1998) , 10.1046/J.1432-1327.1998.254209.X
M. Pagano, R. Pepperkok, F. Verde, W. Ansorge, G. Draetta, Cyclin A is required at two points in the human cell cycle. The EMBO Journal. ,vol. 11, pp. 961- 971 ,(1992) , 10.1002/J.1460-2075.1992.TB05135.X
Hideo Nishitani, Zoi Lygerou, Takeharu Nishimoto, Paul Nurse, The Cdt1 protein is required to license DNA for replication in fission yeast. Nature. ,vol. 404, pp. 625- 628 ,(2000) , 10.1038/35007110
Giovanni Bosco, Wei Du, Terry L. Orr-Weaver, DNA replication control through interaction of E2F–RB and the origin recognition complex Nature Cell Biology. ,vol. 3, pp. 289- 295 ,(2001) , 10.1038/35060086
Alexander Brehm, Eric A. Miska, Dennis J. McCance, Juliet L. Reid, Andrew J. Bannister, Tony Kouzarides, Retinoblastoma protein recruits histone deacetylase to repress transcription Nature. ,vol. 391, pp. 597- 601 ,(1998) , 10.1038/35404
Hiroshi Tanaka, Hirofumi Arakawa, Tatsuya Yamaguchi, Kenji Shiraishi, Seisuke Fukuda, Kuniko Matsui, Yoshiki Takei, Yusuke Nakamura, A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage Nature. ,vol. 404, pp. 42- 49 ,(2000) , 10.1038/35003506
Jean Y.J. Wang, Erik S. Knudson, Peter J. Welch, The Petinoblastoma Tumor Suppressor Protein Advances in Cancer Research. ,vol. 64, pp. 25- 85 ,(1994) , 10.1016/S0065-230X(08)60834-9