Relationship between calcineurin inhibition and plasma endothelin concentrations in cyclosporine-A-treated kidney transplant patients

作者: M. B�chler , P. Leibenguth , C. Le Guellec , A. Carayon , H. Watier

DOI: 10.1007/S00228-004-0860-Y

关键词: CiclosporinCalcineurinEndothelin receptorPharmacodynamicsInternal medicineEndocrinologyKidneyPharmacokineticsEndothelinsChemistryTransplantation

摘要: Objective The inter-individual variability of cyclosporine (CsA) pharmacokinetics is well known. However, there obviously also an pharmacodynamic variability, which might be explored by the measurement biomarkers CsA effects.

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