作者: M. B�chler , P. Leibenguth , C. Le Guellec , A. Carayon , H. Watier
DOI: 10.1007/S00228-004-0860-Y
关键词: Ciclosporin 、 Calcineurin 、 Endothelin receptor 、 Pharmacodynamics 、 Internal medicine 、 Endocrinology 、 Kidney 、 Pharmacokinetics 、 Endothelins 、 Chemistry 、 Transplantation
摘要: Objective The inter-individual variability of cyclosporine (CsA) pharmacokinetics is well known. However, there obviously also an pharmacodynamic variability, which might be explored by the measurement biomarkers CsA effects.