BREAST CANCER IN AUSTRALIAN WOMEN UNDER THE AGE OF 40

摘要: Objectives: A case-control-family study of breast cancer in women under the age 40 was carried out Melbourne and Sydney, Australia, from 1992 to 1995 determine risk factors for these women. Subjects included 467 incident cases identified by state registries 408 population-based controls. Methods: All participants completed a structured risk-factor questionnaire family pedigree during an in-person interview. Where possible, cancers first- second-degree relatives were verified. Results: Multiple logistic regression analysis showed that strongest factor history disease - having at least one affected first-degree relative trebled (relative [RR] = 3.3, 95 percent confidence interval [CI] 1.9-5.8). Risk increased with height three (standard error [SE] percent) per cm, after adjusting height, there evidence decreased weighing 73 kg or more. There first full-term birth (RR 1.8, CI 1.0-3.5) but this fell 30 (SE 11 each subsequent livebirth. Conclusions: The effects other reproductive oral contraceptive use, although not nominally significant, accord published findings similar studies young This Australian has indicated some differ those reported older either direction (e.g., weight) importance history).