Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.

作者: Michael J. Pinkoski , Marita Hobman , Jeffrey A. Heibein , Kevin Tomaselli , Feng Li

DOI: 10.1182/BLOOD.V92.3.1044

关键词: GranzymeBiologyCellular immunityPerforinCytotoxic T cellIntracellularCytoplasmGranzyme BCell biologyFluorescein isothiocyanate

摘要: … Despite extensive attempts, we have not been able to detect granzyme B activity in the supernatant or granzyme B protein on the surface of transfected COS cells. Thus, we believe that …

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